Alpha-1 Antitrypsin Deficiency refers to a disorder or disease that is the result of lack of production or abnormal production of the alpha-1 antitrypsin, an enzyme inhibitor, in the body. Alpha-1 antitrypsin belongs to a family of proteins called as the serine proteinase inhibitor (serpin) family due to similar functions. Such proteins actively aids in managing the inflammation, coagulation, and restore mechanisms of the body. The liver is the major producer of alpha-1 antitrypsin.
In the tissues and blood, there exist some powerful enzymes called as proteases that are capable of attacking unknown substances such as tobacco smoke, present or entering in the body. But, these protease enzymes should be controlled, as they have the potential to attack and harm normal body tissues; instead of the targeted substances. This leads to the [...]
